颅面部静脉畸形的无水乙醇介入硬化治疗

DSA-guided percutaneous ethanol injection sclerotherapy for venous malformations in craniofacial region

目的总结无水乙醇介入硬化治疗颅面部静脉畸形的经验。方法 130例颅面部静脉畸形患者,均采用DSA监视下经皮穿刺无水乙醇硬化治疗。结果 130例患者共接受硬化治疗275次(1～18次/例),平均2.1次/例;单次治疗中的无水乙醇用量为0.5～40ml/次(平均10.3ml/次)。随访时间为5～25个月(平均16个月)。95例治愈,30例明显缓解。结论无水乙醇介入硬化治疗颅面部静脉畸具有肯定疗效。

Objective To evaluate the therapeutic effects of DSA-guided percutaneous ethanol injection sclerotherapy for venous malformations located in craniofacial region. Methods Under DSA guidance, percutaneous ethanol injection sclerotherapy was performed in 130 consecutive patients with venous malformations located in the craniofacial region. Both preoperative and postoperative MRI exams were carried out to evaluate the therapeutic results. A follow-up observation was made and the clinical results were analyzed. Results A total of 275 ethanol injections were employed in 130 patients. The procedures received by each patient varied from one to 18 times, with a mean of 2.1 times. The ethanol dose used in one session was 0.5 ～ 40 ml （mean 10.3 ml）. The follow-up period ranged from 5 to 25 months, with a mean of 16 months. Complete cure was obtained in 95 patients and marked improvement in 30 patients. No severe complications occurred. Conclusion DSA-guided percutaneous ethanol injection sclerotherapy has reliable therapeutic effects for venous malformations located in craniofacial region.