射频消融联合支气管动脉灌注多西他赛治疗非小细胞肺癌的临床应用

Clinical application of radiofrequency ablation combined with bronchial artery infusion of docetaxel in treating non-small cell lung cancer

目的总结冷极射频消融(RFA)联合支气管动脉灌注多西他赛治疗非小细胞肺癌的疗效。方法对21例经CT引导下穿刺活检或支气管镜下获取组织,并经病理学检查所证实的肺癌患者先行冷极RFA治疗,1周后再行经皮支气管动脉灌注多西他赛,观察疗效。结果本组21例患者治疗后病灶全部缩小,临床症状明显改善。结论 RFA和动脉灌注化疗联合应用,操作简便安全,可重复性强,疗效显著,值得临床应用推广。

Objective To discuss the clinical application of radiofrequency ablation combined with bronchial artery infusion of docetaxel in treating non-small cell lung cancer and to summarize the experience of using this therapy in clinical practice. Methods Radiofrequency ablation was performed in twenty-one patients with lung cancer. The diagnosis was confirmed by CT-guided percutaneous needle biopsy or bronchoscopic biopsy in all patients. One week after radiofrequency ablation treatment, bronchial artery infusion of docetaxel was conducted. The therapeutic results were observed and evaluated. Results After the treatment, the lesion’s size was markedly reduced and the clinical symptoms were dramatically improved in all patients. Conclusion Radiofrequency ablation combined with bronchial artery infusion of docetaxel is a safe, effective and simple technique with excellent therapeutic results for the treatment of non-small cell lung cancer. It is really worth popularizing this technique in clinical practice.