分裂性手内肌萎缩和年龄的关系

Relationship of Dissociated Small Hand Muscle Atrophy and Age

目的:观察分裂性手内肌萎缩(分裂手)现象是否随着年龄的增长而出现,并分析其原因。方法:对203例健康受试者的拇短展肌和小指展肌的复合肌肉动作电位(CMAP)波幅进行测定,将受试者按年龄段分成3组,以单因素方差分析和线形相关的方法对两者的比值、差值和年龄关系进行统计分析。结果:随着年龄的增长,CMAP波幅比(拇短展肌/小指展肌)和CMAP波幅差(拇短展肌-小指展肌)降低。结论:分裂手现象出现于正常老年人。

Aim： To observe whether the phenomenon of ＂split hand＂ occur with increasing age, and discuss the mechanism of this progressive phenomenon. Methods： Compound muscle action potentials （CAMP） recorded from abductor pollicis brevis（APB） and abductor digiti minimi（ADM） were analyzed in 203 healthy subjects. The subjects were divided into three groups. The possible association between the ratio or difference in CMAP amplitude and age was tested by one-way ANOVA. The possible association between the ratio or difference in CMAP amplitude and age was tested by using linear regression analysis. Results： The ratio and difference between APB and ADM amplitude decrease with increasing age （P〈0.01）. Conclusion： The ＂split hand＂ occurs in normal aging.