胃癌伴黑棘皮病1例

Gastric carcinoma with acanthosis nigricans:a report of one case

本文报道黑棘皮病伴发胃中分化腺癌、肝转移1例,并结合国内已报道的黑棘皮病71例,探讨其与内脏疾病的关系,指出皮肤症状是恶性肿瘤存在的信号,认为恶性黑棘皮病是一种少见的副瘤性皮肤病,与恶性黑棘皮病相关的肿瘤侵袭性强,一旦怀疑诊断此病一定要全面检查寻找原发灶.

We report a case of acanthosis nigricans associated with gastric adenocarcinoma with liver metastasis in the present study.Furthermore,we analyzed 71 cases of acanthosis nigricans reported in China and explored the relationship between acanthosis nigricans and internal organ diseases.We found that skin symptoms might be signs of the presence of malignant tumors.Malignant acanthosis nigricans is a rare paraneoplastic dermatosis.The neoplasms associated with malignant acanthosis nigricans are typically aggressive in nature,mandating an extensive search for the underlying malignancy once the diagnosis of malignant acanthosis nigricans is suspected.