杭州地区19家医院2004～2008年质子泵抑制剂利用分析

Utilization of Proton Pump Inhibitors in 19 Hospitals of Hangzhou Area during the Period of 2004～2008

目的:评价杭州地区19家医院质子泵抑制剂的应用情况及趋势,为该类药物的研发、生产、销售和临床应用提供参考。方法:统计杭州地区19家医院2004～2008年质子泵抑制剂的销售金额、用药频度和限定日费用。结果:5年来该地区医院质子泵抑制剂的销售金额、用药频度均大幅增长,口服奥美拉唑(包括胶囊和片剂)的用量最大、增长平稳,新一代质子泵抑制剂雷贝拉唑和埃索美拉唑用量增长迅速。结论:质子泵抑制剂是一类很有发展潜力的药物,奥美拉唑作为相对成熟的质子泵抑制剂,在临床应用仍最为广泛。

OBJECTIVE：To investigate situation and trend of proton pump inhibitors in 19 hospital of Hangzhou area and to provide reference for the research,production,sales and clinical application of this kind of drugs. METHODS：Utilization of proton pump inhibitors in 19 hospital of Hangzhou area during the period of 2004～2008 were analyzed statistically in respect of consumption sum,DDDs and DDC. RESULTS：Both consumption sum and DDDs of proton pump inhibitors increased quickly in recent five years. Amount of oral omeprazole（capsule and tablet）was the greatest among those categories and increased steadily. Amount of rabeprazole and esomeprazole as new type of proton pump inhibitors increased rapidly. CONCLUSION：Proton pump inhibitors have great potential for development. Omeprazole are widely used in the clinic as mature proton pump inhibitors.