罗哌卡因骶管运动阻滞的半数有效浓度探讨

Discussion on EC50 of Ropivacaine Caudal Motor Block

目的:探讨罗哌卡因骶管运动阻滞的半数有效浓度(EC50)。方法:用序贯试验法测定罗哌卡因骶管运动阻滞的EC50。结果:罗哌卡因骶管运动阻滞的EC50值为0.22%(95%可信区间为0.216%～0.235%)。结论:骶管注射浓度0.20%～0.22%的罗哌卡因适合门诊膀胱镜检查。

OBJECTIVE：To discuss the median effective concentration（EC50）of ropivacaine caudal motor block. METHODS： The EC50 of ropivacaine caudal epidural block was determined with sequential experimental method. RESULTS：The EC50 of ropivacaine caudal block was 0.22%（95%CI ranged from 0.216% to 0.235%）. CONCLUSION：Canales sacralis injected with 0.20%～ 0.22% ropivacaine is suitable for bladder endoscopic examination in out-patient.