江苏省居民膳食毒死蜱农药暴露评估

Acute dietary chlorpyrifos exposure assessment among people in Jiangsu province

目的了解和评估江苏省居民膳食毒死蜱农药暴露情况。方法整合江苏省居民24h膳食回顾调查和农产品毒死蜱监测数据,运用2种模型估算毒死蜱暴露量,评价膳食风险。结果点评估毒死蜱长期和短期暴露量分别为每天6.05,17.47μg/(kg.bw),分别低于每日允许剂量(ADI)和急性参照剂量(ARfD);食物贡献度前3位为油菜(38.29%)、桃子(24.24%)和菠菜(11.73%);各年龄组暴露风险指数均<100;简单分布评估人群暴露量范围为每天0.00～8.80μg/(kg.bw),暴露量中位数、均值分别为每天0.05,(0.23±0.53)μg/(kg.bw),均低于ADI和ARfD;各年龄组间暴露量差异有统计学意义(P<0.0001),暴露量随年龄增加而降低。结论江苏省居民膳食毒死蜱暴露水平可接受,但儿童暴露值得重视,叶菜类蔬菜和水果的毒死蜱残留仍需降低。

Objective To estimate acute dietary chlorpyrifos exposure among the people in Jiangsu province.Methods According to point estimation and simple distribution,the dietary chlorpyrifos exposure was calculated based on food consumption data from a 24 hours dietary recall survey in Jiangsu province in 2002 and the chlorpyrifos contamination data of 2003-2006 from Jiangsu Agriculture Products Pesticides Monitoring System.Then the results were compared with the acute reference dose（ARfD） for chlorpyrifos established by the Joint FAO/WHO Meeting on Pesticide Residues（JMPR） to assess the hazard.Results The results of point estimation and simple distribution were 17.47 μg/kg·bw·d and 8.80μg/kg·bw·d,both below the ARfD.The mean dietary chlorpyrifos exposure of different age groups ranged from 0.2 to 0.49ug/kg·bw·d.The exposure of younger age group was higher than that of older age group.Conclusion The acute dietary chlorpyrifos exposure in Jiangsu province is within the safety limit.But the higher chlorpyrifos exposure of children,especially younger age groups should be concerned about.