磁性核壳介孔氧化硅微球的制备与应用

Preparation and Application of Silica Microspheres with Magnetic Core/Mesoporous Silica Shell

磁性核壳介孔氧化硅微球作为一种新型功能复合材料,已成为众多研究领域中的一个研究热点。本文综述了近年来利用模板法合成磁性核壳介孔氧化硅微球的研究进展,重点阐述了溶胶-凝胶法和微乳液法在实心微球和中空微球制备中的应用;介绍了磁性介孔二氧化硅微球在蛋白质、DNA分离、靶向药物传输等生物医学上的应用,以及在磁性酸催化、加氢催化、纳米贵金属催化、光催化等催化领域的应用,并对其未来的发展趋势做了展望。

As one new functional composite material,Silica microspheres with magnetic core/mesoporous shell structure have become one research focus of many areas.The authors reviewed the recent synthesis research of silica microspheres with magnetic core/mesoporous shell structure by template.More importantly,the sol-gel process and microemulsion method,which demonstrate applications on solid microspheres and hollow microspheres,are mainly discussed.The biomedicine applications of the magnetic silica microspheres,such as protein or DNA separation,targeted drug delivery are described.Furthermore,in catalysis field,such as magnetic acid catalysis,hydrogenation catalysis,nano noble-metal catalysis,as well as prospects of its development trend are illustrated.