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胃癌患者血清乙醇脱氢酶活性的变化及临床意义

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摘要 目的 探讨血清乙醇脱氢酶(ADH)活性与胃癌的关系,并分析其临床意义.方法 采用NAD+氧化还原酶法检测30例胃癌患者(胃癌组)血清总ADH活性及其同工酶ADH Ⅳ阳性率,并与30例健康志愿者(对照组)进行比较.结果 胃癌组血清总ADH活性及ADH Ⅳ阳性率分别为(23.62士8.44)U/L、83.3%(25/30),均较对照组的(8.92±4.84)U/L、16.7%(5,30)明显上升(P〈0.01);饮酒对胃癌组及对照组血清总ADH活性及ADH Ⅳ阳性率有影响(P〈0.05);但性别对胃癌组及对照组血清总ADH活性及ADH Ⅳ阳性率无影响.结论 血清ADH活性在胃癌患者中有高表达,对胃癌患者的病情监测和预后判断可能具有重要的临床意义.
出处 《中国医师进修杂志》 2010年第16期66-67,共2页 Chinese Journal of Postgraduates of Medicine
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