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治疗性乙型肝炎疫苗研究进展

Research advances in therapeutic vaccination against hepatitis B virus
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摘要 全球范围内有超过4亿慢性乙型肝炎病毒携带者,这些患者发展为肝硬化和肝癌的危险性较大。现有疗法不能长期控制大多数患者的病毒复制,而治疗性乙型肝炎疫苗因其独特的优点正成为新的研究热点。此文就治疗性乙型肝炎疫苗的分类及最新研究进展加以综述。 More than 400 million people in the world are now chronically infected with hepatitis B virus(HBV). For these patients, there is a high risk to develop cirrhosis and hepatocellular carcinoma. Currently available therapies fail to control viral replication for a long time in most patients. Vaccine therapy has recently shown a unique advantage and become the development focus for treatment of patients with chronic HBV infection. This paper reviews the classification and recent research progress of therapeutic HBV vaccines.
出处 《国际生物制品学杂志》 CAS 2010年第3期148-152,共5页 International Journal of Biologicals
关键词 肝炎疫苗 乙型 治疗 肝炎表面抗原 乙型 肝炎核心抗原 乙型 Hepatitis B vaccines Therapy Hepatitis B surface antigens Hepatitis B core antigens
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  • 1Fu-Sheng Wang Li-He Xing Ming-Xu Liu Chuan-Lin Zhu Hui-Gang Liu Hui-Fen Wang Zhou-Yun Lei Division of Biological Engineering,~2 Fourth Department of Liver Diseases,Beijing Institute of Infectious Diseases,Beijing Hospital of Infectious Diseases,Beijing 100039,China.Dysfunction of peripheral blood dendritic cells from patients with chronic hepatitis B virus infection[J].World Journal of Gastroenterology,2001,7(4):537-541. 被引量:131
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