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白三烯B4在婴幼儿毛细支气管炎发病中的作用

Role of leukotriene 114 in infant bronchiolitis
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摘要 目的探讨白三烯B4在婴幼儿毛细支气管炎发病中的作用。方法采用平衡组设计方案,将符合病例纳入标准的50例临床病例为实验组,正常健康体检的50名婴幼儿为对照组。其中实验组采用治疗前后自身对照,分别于治疗前、后做血清中白三烯B4水平的检测,分别与对照组血清中白三烯B4水平作对比。结果婴幼儿毛细支气管炎患儿血清中白三烯B4水平治疗前明显高于治疗后,且治疗前、后血清中自三烯B4水平均明显高于对照组。结论白三烯B4是毛细支气管炎发病中的炎性介质之一。 Objective To investigate the role of leukotriene IM in infant bronchiolitis. Methods Adopting the design plan of balanced set, 50 clinical cases according with internalized standard were the experimental group ,50 infants of healthy physical examination were the control group. Experimental group adopting own controL, concentration of Serum leukotriene B4 in pre-therapy and post-treatment were measured by ELISA respectively and were contrasted with that of the control group. Results Concentration of Serum leukotriene B4 in experimental group in pre-therapy were obviously higher than that in post-treatment, they were obviously higher than that of the control group. Conclusion Leukotriene B4 is one of mediators of inflammation in infant bronchiolitis.
作者 梁玉 刘郴州
出处 《中国临床实用医学》 2010年第6期45-46,共2页 China Clinical Practical Medicine
关键词 白三烯B4 毛细支气管炎 婴幼儿 Leukotriene B4 Bronchiolitis Infants
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