糖尿病患者高敏C反应蛋白与糖尿病肾病的关系研究

Diabetes,high-sensitivity C-reactive protein in patients with diabetic nephropathy studies

目的分析糖尿病患者高敏C反应蛋白（hs-CRP）与糖尿病肾病（DN）的相关性及临床意义。方法将本院120例糖尿病患者按24h尿微量自蛋白（MAU）分为3组，每组40例，并按不同临床检测方法分别进行分析总结。结果血清hs．CRP水平与FBG、TC、TG、MAU、高血压呈正相关。与BMI、Scr、FIB等指标的相关性不显著。结论高敏C反应蛋白与糖尿病肾病发病重要因素之一，随着糖尿病肾病进展，高敏C反应蛋白会水平逐渐随着升高。

Objective To analyze patients with diabetes high-sensitivity C-reactive protein （hs-CRP） and diabetic nephropathy（DN） the correlation and clinical significance. Methods 120 cases of diabetes in our hospital by 24 h urinary microalbumin（MAU） were divided into three groups of 40 people, according to the different clinical detection methods separately analyzed and summarized. Results Serum hs-CRP level FBG, TC, riG, MAU,high blood pressure positively correlated. And BMI, Scr, FIB and other indicators of the relevance is not significant. Conclusion The high-sensitivity C-reactive protein and an important factor in pathogenesis of diabetic nephropathy with diabetic nephropathy progress, high-sensitivity C-reactive protein level gradually as the increase will be.