摘要
Ｇｅｓｔｏｄｅｎｅ是避孕药物１８甲基炔诺酮的衍生物，动物实验表明它的孕激素活性为１８甲基炔诺酮的３～５倍．本文采用各种２ＤＮＭＲ技术，包括：１Ｈ１ＨＣＯＳＹ，１Ｈ１３ＣＣＯＳＹ和ＨＭＢＣ等，归属了它的１Ｈ和１３Ｃ的谱线。
In this article, 1H and 13 C NMR spectra of Gestodene were analyzed by using two dimensional 1H 1H COSY, heteronuclear 1H 13 C shift correlation and HMBC, It was made possible to assign 1H and 13 C NMR spectra of Gestodene completely by combination of these techniques, Gestodene showed complex 1H signal around 1.4-2.6ppm and 13 C signals around 25.3-38.13ppm, This combination of techniques is applicable for assignment of highly overlapping signals, The HMBC spectra can provide valuable information for assignment of 1H and 13 C NMR signals,
出处
《波谱学杂志》
CAS
CSCD
北大核心
1999年第1期65-70,共6页
Chinese Journal of Magnetic Resonance
