手性氨基酸钛螯合物的合成

The Synthesis of Chiral Titanium Chelates from Tosyl - L - amino - acids

用L-对甲苯磺酰氨基酸分别与四氯化钛反应,首次合成了五种L-对甲苯磺酰氨基酸钛化合物。NMR、IR和元素分析数据表明这五种手性钛化合物的结构分别是2a～2d和4,对甲苯磺酰氨基酸钛化合物在惰性气氛中可以保存数周。

Chiral titanium chelates were prepared from tosyl - L - phenylalanine, tosyl - L - valine, tosyl - L- leucine, tosyl - L - iso - leucine and tosyl - L - proline. Their structures were determined to be chiral titanium chelates 2a,2b,2c,2d,and 4 by NMR,IR and elemental analysis. The physical constants of the chiral titanium chelates were reported.