Study on the Location of the Activated Cerebellum Regions in Manual Movement Related to Handedness

The present study used functional magnetic resonance imaging （fMRI） to study the activated site in the cerebellum during bi-hand movement and uni-hand movement, and the lateralization of the cerebellum in hand movement. The coordinates of the peak activation in the CRB were compared using statistical tests, and the results in the primary motor cortex （PMC） were presented as comparison. The results showed a significant difference in cerebellum during bi-hand movement comparing the right-handed with the left-handed subjects. When comparing the right-handed subjects and left-handed subjects during right-hand movement, the significantly different coordinate in dorsal/ventral orientation was observed. The results also showed the different activated site during bi-hand movement and non-dominant hand movement. Our study took the point of view of the lateralization in cerebellum, and the results demonstrated the different site of the peak activation in cerebellum during bi-hand movement and uni-hand movement, which suggested that the handedness also existed in the cerebellum.