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生物蛋白胶联合金因肽在肝创面中的应用价值 被引量:1

Combined using of fibrin glue and recombinant human epidermal growth factor for the surface of liver
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摘要 目的评价医用生物蛋白胶与金因肽联合应用于肝脏创面预防出血和胆瘘的效果。方法取32例肝脏手术后肝组织创面渗血病人作为实验组,将金因肽及医用生物蛋白胶局部联合应用于肝脏创面;取同期21例病人做对照组,对比观察其创面愈合效果。结果实验组32例病人术中出血量较对照组减少[(350.3±12.52)ml VS(572.5±18.75)ml,P<0.05];术后第一天引流量较对照组减少[(93.2±11.15)ml VS(162.6±25.39)ml,P<0.05];实验组术后拔除引流管时间较对照组短(2.0±1.50天VS 5.0±4.09天,P<0.05)。结论医用生物蛋白胶与金因肽联合应用具有良好的防止肝脏创面出血及胆瘘的发生,促进创面愈合,无不良反应发生。 Objective To evaluate the effect of combined application of FG and EGF to prevent liver raw surface from bleeding and biliarty fistula.Method 32 patients with wound oozing after liver surgery were treated with FG and EGF in the liver wound,controlled with 21 patients.Result The blood loss and drainage volume in experimental group was fewer than that in control group(P〈0.05).The time of removal of drainage in experimental group was shorter than that in control group(P〈0.05).Conclusion Combined using of FG and EGF can prevent liver raw surface from bleeding and biliarty fistula,and promote raw surface to heal without adverse effects.
出处 《西部医学》 2010年第6期1006-1007,1010,共3页 Medical Journal of West China
基金 深圳市宝安区科技局计划项目(NO.2008153)
关键词 生物蛋白胶 金因肽 肝脏创面 联合应用 FG EGF Liver raw surface Combined application
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