小儿21三体综合征的脑部CT表现

Cerebral CT Manifestations of 21 Trisomy Syndrome in Children

目的：提高对小儿２１三体综合征脑部ＣＴ表现的认识和诊断。材料与方法：回顾性分析２３例经细胞遗传学检查证实的２１三体综合征的脑部ＣＴ表现。结果：本病的ＣＴ特征为：（１）脑内钙化，多见于基底节区，呈点状或小圆形；（２）侧裂、额顶区蛛网膜下腔增宽；（３）小脑发育不良。结论：本病ＣＴ表现具有一定的特征性，但其ＣＴ诊断须结合细胞遗传学检查确定。

Objective: To improve the understanding and diagnostic ability of the brain changes in 21 trisomy syndrome.Materials and Methods:Cerebral CT findings in 23 cases with 21 trisomy syndrome, proved by cytogenetics, were retrospectively analyzed.Results:CT findings were as follows: (1) spotty or small round calcifications, mainly seen in basal ganglia area; (2) dilated sylvian fissure and subarachnoid cavity in frontal and parietal lobes; (3) underdevelopment of cerebellum.Conclusion: Cerebral CT findings of 21 trisomy are characteristic, however, cytogenous examination should be conducted in order to confirm the diagnosis.