141例临床药物不良反应监测报告统计分析

Clinical Statistical Analysis about 141 Cases of Adverse Drug Reaction Monitoring Report

目的分析药物不良反应(ADR)的发生情况,为临床合理用药提供依据。方法对医院141例ADR报告引发的药品种类、给药途径、临床表现等方面进行统计分析。结果共有68个品种引起不良反应,从药物分类统计以抗感染药物的报告例次居首位65例,占46.1%,其次为中药制剂29例,占20.6%;ADR病例中联合用药占83.7%;以静脉途径用药为主占75.9%;主要的ADR类型为皮肤损害占52.5%,其次是心脑血管系统及泌尿系统损害。结论应加强合理用药,重视中药不良反应,减少不良反应的发生。

Objective To analyze the adverse drug reaction（ADR） occurrence of circumstances,to provide a basis for clinical rational use of drugs. Methods 141 cases of hospital ADR reporting triggered by drug type,route of administration,clinical manifestations in areas such as statistical analysis. Result A total of 68 varieties of adverse reactions from drug classifi cation statistics to report cases of anti-infectives second ranked fi rst 65 cases,accounting for 46.1%,followed by traditional Chinese medicine preparation in 29 cases,accounting for 20.6%;ADR cases,combination therapy accounted for 83.7%;channels mainly by intravenous drug use accounted for 75.9%;the main types of ADR for the skin lesions accounted for 52.5%,followed by cardio-cerebral vascular system and urinary system damage. Conclusions Should be to enhance rational drug use,attach importance to traditional Chinese medicine adverse reactions,to reduce the incidence of adverse reactions.