双水平无创正压通气在治疗慢性阻塞性肺疾病合并呼吸衰竭疗效观察

Observation of Clinical Effects of chronic obstack Pulmonary Disease Combined with Type Respiration Failure by BiPAP

目的:探讨应用双水平无创正压通气(BiPAP)在慢性阻塞性肺疾病(COPD),合并呼吸衰竭与常规呼吸内科治疗的疗效对比。方法:70例入选患者随机分为治疗与对照二组,每组35例,在常规治疗一致下,治疗组加用双水平无创正压通气(BiPAP)治疗,5天为一治疗阶段,观察患者5天后的症状体征及pH PaO2 PaCO_2指标变化,并与对照组在血气分析各数值间做统计学分析。结果:BiPAP治疗组患者临床症状、体征和血气指标在治疗后较治疗前明显改善(pH PaO_2 PaCO_2 P值均<0.05),治疗后与对照组治疗后的血气指标有统计学意义(各P值均<0.05)。结论:BiPAP通气支持治疗COPD合并呼吸衰竭疗效显著。

Objective： To evaluate the clinical effects of chronic obstacle pulmonary disease combined with II type respiration failure between routine treatment and BiPAP, Methods： 70 patients were randomly distributed into two groups. Which were control group and BiPAP group, Each group had 35 patients, BiPAP group added ventilation treatment besides the same routine treatment, the time was about three to five days, finally we observed the change of symptoms and physical characters and the index of pH PaO2 PaCO2,and compare the index of pH PaO2 PaCO2 with control group by statistics. Results ： compared to before treatment, the blood gas index and symptoms and physical characters of BiPAP group had improved obviously after treatment（P 〈 0.05）,and we also found that there was significant statistic difference in the blood gas index after treatment between control group and BiPAP group（P 〈 0.05）, Conclusions： The treatment of chronic obstacle pulmonary disease combined with II type respiration failure with BiPAP can bring better clinical effects.