摘要
通过正交试验设计,以Td值为指标,优选出吉非罗齐胶囊的最佳处方组成为:每粒含吉非罗齐0.3g,淀粉0.01g,低取代羟丙纤维素0.015g,新配方胶囊的溶出度显著优于原产品。
By orthogonal design with T d as index,the optimal formula of gemfibrozil capsules
was 0.3g gemfibrozil,0.01g starch and 0.015g L HPC in every capsule. The dissolution of
capsules with new formula was much better than that of the old ones.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1999年第3期118-120,共3页
Chinese Journal of Pharmaceuticals
关键词
吉非罗齐
正交试验
溶出度
胶囊
gemfibrozil,
orthogonal design, dissolution, capsules