腹水超滤回输联合多巴胺及速尿治疗肝硬化顽固性腹水41例分析

41 cases of ascites reinfusion ultrafiltration combined dopamine and furosemide treatment of liver cirrhosis with refractory ascites analysis

目的探讨腹水超滤浓缩回输联合多巴胺及速尿治疗顽固性肝硬化腹水的疗效。方法将81例患者随机分为两组,治疗组41例,采用腹水浓缩超滤回输联合多巴胺及速尿治疗,对照组40例,以常规补充清蛋白、限钠、限水、利尿治疗为主,比较两组疗效,同时观察治疗组治疗前后患者尿量、腹围、血清清蛋白、血钾,血钠的变化。结果治疗组疗效优于对照组(P<0.01)。与治疗前比较,治疗组治疗后尿量、血清清蛋白水平明显增加,腹围减少(P<0.05),血钾、血钠则无明显变化。结论腹水浓缩回输联合多巴胺及速尿治疗顽固性腹水疗效显著,可在临床酌情使用。

Objective To investigate the ascites reinfusion uhrafihration combined dopamine and furosemide treatment of intractable ascites due to cirrhosis of the effect. Methods 81 cases were randomly divided into two groups, treatment group, 41 patients with ascites ultrafihration concentrate reinfusion combined dopamine and furosemide treatment, the control group of 40 patients with conventional supplement albumin, sodium restriction, fluid restriction, diuretic therapy for Lord, compare the efficacy of two groups, while observing the treatment group before and after treatment in patients with urine output, abdominal circumference, serum albumin, serum potassium, serum sodium change. Results The results of the treatment group more effective than the control group （ P 〈 0.01 ）. Compared with those before treatment, after treatment, urine volume, serum albumin levels were significantly increased, reduction in abdominal circumference （P 〈 0.05 ）, serum potassium, sodium had no significant changes. Conclusion Ascites reinfusion combined dopamine and furosemide treatment of intractable ascites significant, could be in clinical use, as appropriate.