摘要
目的了解食物特异性IgG与儿童多动症(ADHD)之间的关系。方法将30例ADHD患儿随机分为两组,A组予利他林治疗,B组根据食物特异性IgG检测结果行限制饮食。应用多动症评分量表比较治疗5周后症状改善情况。结果 A、B组患儿在治疗后多动症评分均减低(P<0.05),症状改善率分别为(70±13)%和(57±18)%(P>0.05)。A组发生失眠、厌食各1例。结论根据食物特异性IgG检测结果行限制性饮食可明显改善儿童多动症状,提示食物特异性IgG可能参与ADHD发病机制。
Objective To evaluate the relationship between food specific IgG(sIgG) and attention deficit/hyperactivity disorder(ADHD).Methods Thirty cases of ADHD children were randomly divided into ritalin group(14 cases) and sIgG-positive food restriction group(16 cases).The curative effects were evaluated by clinical ADHD index after 5 weeks' treatment.Results ADHD index after treatment was significantly lower than that before in both groups(P0.05).The rates of symptom improvement were(70±13)% and(57±18)%,respectively(P0.05).One case complained of insomnia and one case had anorexia in ritalin group.Conclusion Food sIgG may be involved in the pathogenesis of ADHD,food restriction can ameliorate the symptom of ADHD.
出处
《山东医药》
CAS
北大核心
2010年第24期18-19,共2页
Shandong Medical Journal
基金
首都医学发展基金联合攻关项目(2007-390)
关键词
儿童多动症
食物特异性IGG
利他林
attention deficit/hyperactivity disorder
food specific IgG
ritalin