3,4,5-三甲氧基苯胺的合成
Synthesis of 3,4,5-trimethoxyaniline
摘要
以没食子酸为原料,经甲基化、硝化、还原等反应,合成了标题化合物,总收率44.9%。
3,4,5-Trimethoxyaniline was synthesized through methylation,nitration,and reduction reactions using gallic acid as the starting material.The total product yield was 44.9%.
出处
《化学试剂》
CAS
CSCD
北大核心
2010年第6期559-560,共2页
Chemical Reagents
基金
贵州民族学院科学基金资助项目(2009-YJRC01)
参考文献6
-
1KOZAK I, KRONRAD L, PROCHAZKA M. Synthesis of gallic acid (-^14 COOH ) [ J ]. J. Labelled Compd. Radiop- harm. , 1978,15 ( S1 ) :401-405.
-
2PIETERSE K. Electron-deficient materials based on azaheterocycles [ D ]. 2001 , Eindhoven : Technische Universiteit Eindhoven,ISBN 90-386-2902-8.
-
3JOULLIE M, MAILLARD G, LAKAH L, et al. Therapeutically useful 3,4, 5-trimethoxybenzene derivatives: US, 4 252 804[ P]. 1981-02-24.
-
4PETTIT G., CHAMBERLAND M, GREEN B. Antineoplastic agents. XIX. N-bis (2-haloethyl) glycine amides [J] Can. J. Chem. ,1967,45(10) :1 555-1 560.
-
5MAUTHNER F, CLARKER H T. Organic synthesis collection[ M ]. GILMAN H. Vol. 1, Ed. New York: Wiley, 1941:537.
-
6HUGHES G K, NEILL K G, RITCHIS E. The synthesis of melicopicine and some trimethoxy-10-methylacridones [J] . Aust. J. Sci. Res. Set. A,1950, 3(3) :497-503.
-
1罗成,曹威,龚小伦,郭文勇,沈玉芳.3,4,5-三甲氧基苯胺的合成[J].化学与生物工程,2010,27(7):51-53.
-
2曹胜利,冯玉萍,张玫,蒋宇扬,宇小青,莫卓华.4(3H)-喹唑啉酮芳胺衍生物的合成及其抗肿瘤活性评价[J].应用化学,2007,24(2):162-167. 被引量：4
