摘要
为了研究腺苷酸环化酶（ＡＣＬ）对糖原型胃癌糖代谢的影响，采用光镜、电镜和酶细胞化学技术研究了５６例糖原型和非糖原型胃癌的形态学和ＡＣＬ活性。发现糖原型胃癌ＡＣＬ活性明显下降。可以认为ＡＣＬ活性下降导致癌细胞信号传导途径中第二信使ｃＡＭＰ产生障碍。
Light and electron microscopies and enzyme cytochemistry were applicated to detect adenylate cyclase(ACL) activity of 56 cases of gastric cancer.The results showed that ACL activity in glycogen type gastric cancer was obviously decreased.It is suggested that ACL activity deficiency may be responsible for glycogen accumulation in glycogen type gastric cancer.
出处
《实用癌症杂志》
1999年第1期16-17,共2页
The Practical Journal of Cancer
关键词
胃癌
糖原
腺苷酸环化酶
酶细胞化学
Gastric cancer Glycogen Adenylate cyclase Enzyme cytochemistry
