垂体区转移癌的诊断和治疗

Diagnosis and Treatment of the Metastases in Sella Turcica

报道２例首发症状分别为尿崩症、眼外肌麻痹的鞍区肿瘤病例，经手术治疗，病理诊断为垂体区转移癌，其原发肿瘤为肺癌，术后预后不良。对出现尿崩症、眼外肌麻痹、视力明显下降、垂体功能低下症状而年龄较大的患者，当ＭＲＩ检查蝶鞍区有不规则呈侵蚀性生长肿物时，应首先考虑垂体区恶性肿瘤的诊断，并检查有无原发癌肿。对于诊断不明者可考虑手术探查，以明确诊断及缓解症状。

Two cases of metastases in sella turcica were reported.They were 49 and 72 years old,diabetes inspidus or extraocular nerve palsy was the first symptom. The diagnosis was confirmed by operation and pathology.The original tumors were in lung.Both of them died in 61 or 67 days postoperation.The diagnosis and treatment of metastases in sella turcica were discussed.Authors consider that it could be malignant tumors in sella turcica when older patients have diabetes inspidus,extraocular nerve palsy,visual field deficit or hypopituitarism,especially when these symptoms deteriorate in a short time and when MRI show sella turcica tumors are invading and irregular.The original cancers should be checked in other systoms.Operation may be taken to definite diagnosis and to remove tumor.But it should not be appropriate in patients with general metastases.