微量间歇雾化吸入疗法辅助治疗婴幼儿重症肺炎的效果研究

The effect of improved inhalation therapy as adjuvant treatment for infants with severe pneumonia

目的探讨微量间歇雾化吸入疗法辅助治疗婴幼儿重症肺炎的效果。方法将148例重症肺炎婴幼儿随机分成观察组和对照组各74例，观察组施行微量间歇雾化吸入疗法，根据患儿年龄、憋喘程度选择适合的雾化吸入时间和间歇时间。对照组按传统持续雾化吸入法进行操作。观察两组患儿雾化吸入前后呼吸、心率、血氧饱和度和血气分析指标、憋喘程度和治疗效果比较。结果两组雾化吸入前呼吸、心率、末梢血氧饱和度和血气分析指标及憋喘程度均无差异（P〉0．05），而雾化吸入后呼吸、心率、末梢血氧饱和度、血气分析指标、憋喘程度差异均有统计学意义（P〈0．05），观察组治疗效果优于对照组（P〈0．01）。结论微量间歇雾化吸入疗法是促进组织有效供氧，改善通气和氧合功能及患儿血气结果，缓解不同程度的憋喘，缩短病程，显著提高治疗效果。

Objective To investigate the effect of improved therapy-trace intermittent inhalation therapy as the adjuvant treatment for infants and children with severe pneumonia. Methods A total of 148 cases of infants and children with severe pneumonia were randomly divided into test group and control group, each group contained 74 patients. We used trace-intermittent inhalation therapy for the test group and selected the appropriate inhalation time and intermittent time according to children＇ s age and the degree of choke gasp. In the control group, we used the traditional continuous inhalation method. Breathing, heart rate, oxygen saturation, indicators of blood gas analysis and the extent of choke before and after inhalation were compared. Results The two group showed no differences in breathing, heart rate, oxygen saturation, indicators of blood gas analysis and the degree of choke before inhalation （ P 〉0. 05 ） , while significant difference were showed after inhalation （ P 〈 0. 01 ）, and the difference of the choke degree was statistically significant （ P 〈 0. 05 ）. This study showed that the trace-intermittent inhalation treatment was significantly superior to the traditional continuous inhalation treatment （ P 〈 0. 01 ）. Conclusions Trace intermittent inhalation therapy can promote the effective oxygen supply of the organization, improve ventilation and oxygenation function and blood gas results in children, relieve the different degrees of choke gasp, shorten the course of disease and improve the therapeutic effect significantly.