新辅助化疗动脉灌注治疗宫颈癌的临床分析

Treatment of cervical cancer with arterial perfusion and neoadjuvant chemotherapy

目的分析宫颈癌术前新辅助化疗—动脉灌注的疗效。方法经病理确诊宫颈癌患者201例,所有患者均行子宫动脉灌注栓塞治疗,其后择期行宫颈癌根治术。结果介入治疗后,完全缓解型(CR)84例、部分缓解型(PR)75例、总有效率为79.1%。同期选择185例宫颈癌直接行手术治疗的患者作为对照组,两组患者一般资料具可比性。结论新辅助化疗—子宫动脉灌注栓塞用于宫颈癌安全有效,有利于肿瘤根治切除。

Objective To analyze the therapeutic effect of arterial perfusion and neoadjuvant chemotherapy on cervical cancer. Methods A total of 201 patients with pathologically-confirmed cervical cancer, enrolled in this study, underwent arterial perfusion and adjuvant chemotherapy followed by radical hysterectomy. Results Complete response（CR）and partial response（PR）were achieved in 84 and 75 cases, respectively, with a total effective rate of 79.1%, which was similar to that of 185 cervical cancer patients as a control group after direct surgical treatment. Conclusion Arterial perfusion and neoadjuvant chemotherapy are a safe and effective treatment modality for cervical cancer and can be used in radical resection of tumors.