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视网膜母细胞瘤Ag~NORs的定量及意义 被引量:1

Ag-NORs IN RETINOBLASTOMA:A QUANTITATIVE STUDY AND ITS PROGNOSTIC IMPORTANCE
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摘要 用银胶染色一步法,对29例视网膜母细胞瘤Ag-NORs进行了定量研究。健康存活组15例平均每个瘤细胞核内Ag-NORs4.78个,死亡组14例平均7.60个,差别具有高度显著性意义(P<0.001)。结果表明,Ag-NORs可成为估计视网膜母细胞瘤预后的有意义的组织学指标。 Using a silver colloid staining technique(one-step method), Nucleolar organizer region-associated proteins(Ag-NORs)have been studied quantitatively in paraffin sections of 29 cases of retinoblastoma.A signifi- cant difference was found between the numbers of Ag-NORs in the nuclei of survival group(a mean of 4.78 per nucleus)and those of dead group (a mean of 7.60 per nucleus)(P<0.001).It is suggested that mean number of Ag-NORs is of prognostic value in retinoblastoma.
出处 《山东医科大学学报》 1990年第3期42-44,共3页 Acta Academiae Medicinae Shandong
关键词 视网膜 母细胞瘤 AG-NORS 病理 Retinoblastoma Nucleolar organizer region-associated proteins Prognosis Pathology
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  • 1D. Ploton,M. Menager,P. Jeannesson,G. Himber,F. Pigeon,J. J. Adnet. Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level[J] 1986,The Histochemical Journal(1):5~14
  • 2W. M. Howell,D. A. Black. Controlled silver-staining of nucleolus organizer regions with a protective colloidal developer: a 1-step method[J] 1980,Experientia(8):1014~1015

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