摘要
建立慢性肾衰贫血大鼠的动物模型后 ,分别用基因重组人红细胞生成素 (r Hu EPO)按 45 0 IU /kg、15 0 IU /kg、 5 0 IU /kg 3组剂量连续 14d皮下注射上述大鼠 ,同时设立阳性对照组及阴性对照组。结果发现r Hu EPO只能治疗肾衰造成的贫血 ,而对肾衰无治疗作用。
The rats with hyphemia caused by chronic renal failure were divided into 3 groups and subcutaneously injected with recombinant human erythropoietin(rHuEPO) for 14 days at the doses of 450, 150 and 50 IU/kg respectively, using EPOGEN(Amgen,USA) and normal saline as control. The rHuEPO showed curative effect on the hyphemia caused by chronic renal failure. However, it showed no effect on chronic renal failure.
出处
《中国生物制品学杂志》
CAS
CSCD
1999年第1期32-35,共4页
Chinese Journal of Biologicals
