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Statine乃其类似物的合成 被引量:2

SYNTHESIS OF STATINE AND ITS ANALOGUES
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摘要 Statine及其类似物存在于一些具有抗肿瘤、抗病毒、抗炎症等生理活性的天然产物之中.本文简要介绍Statine及其类似物的存在及生理活性,并从不同的起始原料出发,介绍它们的立体选择性合成. Statine and some of its analogues are essential constituents of naturally occurring small pep-tide such as pepstatin,cyclic depsiptide. In this paper we give a brife review on bioactivity and natural occurrence of the peptide as well as steroselective synthesis of statine and its analogues from different starting materials.
出处 《天然产物研究与开发》 CAS CSCD 1999年第1期21-26,共6页 Natural Product Research and Development
关键词 STATINE 类似物 抗肿瘤活性 合成 Statine and its analogues,Natural occurrence,Antitumor ,Steroselective synthesis
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  • 1Huang P Q,Tetrahedron:Asymmetry,1999年,10卷,19期,3827页
  • 2Huang P Q,Synth Commun,1998年,28卷,3期,417页
  • 3Huang P Q,Tetrahedron Lett,1998年,54卷,41期,12547页
  • 4Leung D,Abbenante G,Fairlie D P.Protease inhibitors:current status and future prospects[J].J Med Chem,2000,43(3):305-341.
  • 5Ma D,Ma J,Ding W,et al.An improved procedure to homochiral cyclic statines[J].Tetrahedron:Asymmetry,1996,7(8):2365-2370.
  • 6Fehrentz J A,Bourdel E,Califano J C,et al.Synthesis of chiral urethane N-alkoxycarbonyl tetramic acids from urethane N-carboxyanhydrides(UNCAs)[J].Tetrahedron Lett,1994,35(10):1557-1560.
  • 7Hu J,Cwi C L,Smiley D L,et al.Design and synthesis of statine-containg BACE inhibitors[J].Bioorg Med Chem Lett,2003,13(24):4335-4339.
  • 8Jouin P,Castro B.Stereospecific synthesis of N-protected Statine and its analogues via chiral tetramic acid[J].J Chem Soc:Perkin Trans I,1987:1177-1182.
  • 9Yuste F,Diaz A,Ortiz B,et al.A stereodivergent approach to syn-and anti-β-hydroxy-γ-amino acids.Enantioselective synthesis of N-Boc-Statine and N-Boc-3-epistatine mediated by sulfoxides[J].Tetrahedron:Asymmetry,2003,14(5):549-554.
  • 10Rich D H,Sun E T,Boparai A S.Synthesis of (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid derivatives.Analysis of diastereomeric purity[J].J Org Chem,1978,43(18):3624-3626.

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