联合检测CEA、NSE和CYFRA21-1在肺癌诊断中的价值

Clinical significance of Joint measuring CYFRA21-1,CA153 and NSE for lung cancer

目的探讨肿瘤标志物CEA、NSE和CYFRA21-1联合检测对肺癌的诊断价值。方法检测不同病理类型肺癌患者的血清中CEA、NSE和CYFRA21-1水平。结果肺癌组血清CEA、NSE和CYFRA21-1水平明显高于肺良性疾病患者(P<0.05);CEA+NSE+CYFRA21-1诊断灵敏度明显高于单项肿瘤标志物(P<0.05)。结论血清CEA、NSE和CYFRA21-1联合检测有助于肺癌临床诊断。

Objective To investigate the diagnostic value of Joint determination of CEA,NSE and CYFRA21-1 in serum from patients with lung cancer.Methods Detected the CEA、NSE、CYFRA21-1 in different type patients with lung cancer.Results In lung cancer group,the levels of CEA,NSE and CYFRA21-1 were significantly higher than those group of benign lung disease （P〈0.05）.The sensitivity of joint measurement CEA,NSE and CYFRA21-1 was significantly higher than that of each tumor marker（P〈0.05）.Conclusion Joint measurement of CEA,NSE and CYFRA21-1 is helpful to diagnosis of lung cancer.