肾移植术后社区获得性肺炎的病原体分析

Pathogen Analysis of Community Acquired Pneumonia after Renal Transplantation

目的探讨肾移植术后社区获得性肺炎(CAP)的病原体诊断,以提高患者生存率。方法回顾性分析40例肾移植术后CAP患者中肺炎的发生时间、病原学和临床表现。结果肾移植术后CAP的病原体主要有细菌、病毒、真菌、结核几大类;出现时间在术后半年以内居多;曲霉菌及卡氏肺孢子虫肺炎病死率高。结论肾移植术后CAP的病原体以特殊病原体多见,早期准确判断并经验性治疗能明显改善患者的预后。

Objective To investigate pathogen diagnosis of community acquired pneumonia （CAP）and improve the management of pulmonary infection in patients after renal transp1antation. Methods The onset time,pathogen and clinical manifestation of CAP were retrospectively analyzed in 40 patients after renal transp1antation. Results The main etiological microorganisms of CAP were bacterium,virus, fungi or tuberculosis mainly within 6 months. Among them,2 cases had polyinfection. Aspergilli and pneumocystis carinii pneumonia led to high mortality rate. Conclusion Early diagnosis and empirical therapy are very important. The diagnosis and active treatment contribute to the decrease in case fatality.