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辛伐他汀联合依折麦布的临床应用进展 被引量：2

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摘要 心血管疾病与脂质紊乱有着极其紧密的联系,在治疗过程中降低低密度脂蛋白胆固醇（LDL-C）的水平,可以显著降低冠状动脉疾病（CAD）和急性心血管事件的发病率和致死率。他汀类药物有着良好的降LDL—C效果。最近研究还发现，他汀类药物还具有改善血管内皮功能和抗炎的特性，这些都提示他汀类药物可能对动脉粥样硬化也有治疗作用，同时其改善血管功能和凋节炎性反应的作用已经成为了研究的热点。但是，随着他汀类药物的广泛应用，
作者 张力华
机构地区 黑龙江佳木斯中心医院药剂科
出处 《中国药房》 CAS CSCD 北大核心 2010年第24期2298-2300,共3页 China Pharmacy
关键词 临床应用 依折麦布 辛伐他汀 低密度脂蛋白胆固醇 他汀类药物 急性心血管事件 冠状动脉疾病 血管内皮功能
分类号 R917 [医药卫生—药物分析学]
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参考文献20

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同被引文献26

  • 1中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量：5230
  • 2何甲均,徐学广,郑莘.辛伐他汀和盐酸小檗碱治疗高脂血症和颈动脉粥样硬化的疗效[J].天津医药,2007,35(7):539-541. 被引量：3
  • 3中华人民共和国卫生部药政管理局.新药(西药)临床研究指导原则[M].北京:人民卫生出版社,1993:51.
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  • 6Hah YJ, Kim NK, Kim MK, el al. Relationship hetween Chemerin Lords and Cardiometabolic Parameters and Degree of Coronary Stenosis in Korean Patients with Coronary Artery Disease[J]. Diabetes Metab ,1, 2011, 35 (3) = 248 254.
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  • 8Stofkova A. Resistin and visfatin: regulators of insulin sensi tivity, inflammation and immunity[J]. Endocr Regul, 2010, 44(1):25 36.
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  • 10Kadoglou NP, Gkontopoulos A, Kapelouzou A, el al. Serum levels of vaspin and visfatin in patients with coronary artery diseaseKozanistudyJ. ClinChimActa, 2011,412(1 2):48 52.

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中国药房
2010年 第24期

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