摘要
TOR(target of rapamycin)是一种结构和功能高度保守的蛋白激酶,它能够通过整合营养、能量、生长因子等信号调节细胞的增殖、体积增大及细胞周期进程。作者综述了TOR激酶的上下游信号传导途径及氨基酸和能量等营养状况对这些信号传导通路和细胞生长的影响,为探讨营养调控体蛋白合成的机制及精准营养供给技术的建立提供宝贵的理论基础和开创性思路。
TOR（target of rapamycin）,a protein kinase with high conservation in structure and function from yeast to mammalian,controls the cell growth and cycle progress by integrating the nutrient,energy and growth factors.The authors reviewed TOR kinase and the related upstream and downstream signaling pathways,and the regulation of amino acid and energy on these signals and subsequently cell growth,for establishing the mechanism of nutrient regulating protein position and providing a new insight into the technology of exact nutrient provision.
出处
《中国畜牧兽医》
CAS
北大核心
2010年第6期25-29,共5页
China Animal Husbandry & Veterinary Medicine
基金
国家肉鸡产业体系(nycytx-42-G4-03)
