2009年聊城市手足口病流行病学特征分析

Analysis on Epidemiological characteristics of Hand-foot-mouth Disease in Liaocheng City in 2009

[目的]分析聊城市2009年手足口病流行病学特征,为控制手足口病提供科学依据。[方法]收集整理聊城市2009年各级各类医疗机构报告的手足口病卡信息和RT-PCR实验室检测结果,应用描述性方法进行流行病学分析。[结果]2009年聊城市手足口病发病率为277.60/10万,死亡3例,病死率0.02%,3个县出现了手足口病的暴发流行;男性10248例,女性5770例,男女之比为1.8∶1;全市8个县(市、区)均有手足口病报告,各县(市、区)间发病率的差异有统计学意义(P<0.01)。3～9月为发病高峰;病例年龄为2个月至57岁,以小年龄组5岁及以下儿童发病最高15504例,占96.79%。共检测65份样本,EV71阳性率为12.31%,COXA16阳性率为4.62,其他肠道病毒阳性率为61.54%。[结论]2009年聊城市手足口病发病率处于较高水平,对5岁以下年龄组人群应加强手足口病监测工作,同时加强实验室检测。

[Objective] To analyze the epidemiological characteristic of hand-foot-mouth disease（HFMD）in Liaocheng,and provide scientific evidence for controlling and preventing measures.[Methods]Collected the data of hand-foot-mouth disease in Liaocheng in 2009 and analyzed the data by descriptive epidemiology method.Some patients were diagnosed through RT-PCR.[Results]The incidence of hand-foot-mouth disease was 277.60/105 in Liaocheng in 2009.10 248 male cases,5 570 female cases were reported.The ratio between male and female was 1.8∶1.3 died and the case-fatality rate was 0.02%.Three counties appeared outbreak of HFMD.The cases were reported in all counties and districts.There were significant differences of the HFMD incidences among the counties and districts（P0.01）.The peak of hand-foot-mouth disease was from March to September.Patients aged 2 months to 57 years old.cases were less than 5 years old,96.79%.65 specimens were detected.The positive rate of EV71 was 12.3%.[Conclusion]The incidence of HFMD is at a high level in Liaocheng in 2009.HFMD surveillance should be strengthened children less than 5 years old.Pathogen detection should be enhanced.