2例重症手足口病的流行病学调查报告

Epidemiological Study of Two Cases of Hand-Food-Mouth Disease

目的:通过对某一局部集中发生重症手足口病患儿的流行病学调查和实验室检查,了解2008年5月手足口病爆发以来患儿发生手足口病合并病毒性脑膜炎的情况以及患儿是否感染EV71型肠道病毒,向幼托机构提供预防手足口病的相关措施,提醒医院加强病区、门诊管理,防止手足口病的交叉感染。方法:对患儿进行现场流行病学调查,填写手足口病流行病学个案调查表。结果:2例手足口病重症患儿均有流行病学接触史,但无外出史,未饮用不洁水源,实验室检测均为病毒性脑膜炎,咽拭子和肛拭子检出肠道病毒阳性率高,急性期血分离出EV71型肠道病毒。讨论:幼托机构对手足口病的防治措施;医院内部需加强管理,预防交叉感染;医疗机构与疾病控制机构的密切配合。

objectives：Epidemiological study and laboratory examination were preformed focus on 2 severe Hand-Food-Mouth Disease（HFMD）cases,which occur concentrated in one place.TO determine whether EV71 is the right pathogen of HFMD with the complication of viral encephalitis since May Of 2008,provide efficient prevention methods to nursery and kindergarten,alert hospital to strengthen the management of wards and clinic.Methods：Field investigations were carried on for two HFMD patients,and epidemiological study forms were filled by parents.Results：There were HFND epidemiological expose for two patients,no outgoing and contaminated water drinking history,laboratory study of these two cases clue to viral encephalitis,and EV71 were isolated form the throat swabs and anus swabs.Conclusions：Nursery and kindergarten should strengthen the prevention of HFMD;efficient management should executive in hospital;and the disease control and prevent institute and hospital should work in close cooperation.