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手足口病的现状与展望 被引量:69

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摘要 手足口病(hand-foot-mouth disease,HFMD)又称发疹性口腔炎。主要由肠道病毒71型(Enterovirus71,EV71)和柯萨奇A16型(CoxsackieA16,CoxA16)病毒引起的发疹性传染病。多发于5岁以下婴幼儿,引起手、足、口腔等部位的疱疹,口腔黏膜溃疡和四肢末端水疱样皮疹。少数患儿并发心肌炎、肺水肿、急性弛缓性麻痹和无菌性脑膜炎等,严重病例可以致死。夏秋季多发,病毒主要通过肠道途径和日常接触传播,也可通过空气飞沫传播。近年来,我国大部分地区发生了EV71型病毒感染引发的手足口病疫情,出现神经系统和呼吸系统损害,导致部分患儿死亡,并形成流行趋势,引起了社会广泛关注。
作者 邵惠训
出处 《国际病毒学杂志》 2010年第3期74-78,共5页 International Journal of Virology
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参考文献9

  • 1Tu PV,Thao NT et al.Epidemiologic and virologic investigation of hand,foot and mouth disease,Southern Vietnam[J].Emerg Infect Dis,2007,13(11):1733-1741.
  • 2Nilendu Sarma,Abhijit Sarkar et al.Epidemic of hand,foot and mouth disease in West Bengal,India in August,2007.A multicentric study[J].Indian J Dermatology,2009,54(1):26-30.
  • 3Sazaly AI,Ching S et al.Enterovirus 71 outbreak,Brunei[J].Emerg Infect Dis,2009,15(1):79-82.
  • 4Lee TC,Guo HR et al.Diseases caused by Enterovirus 71 infection[J].Podia Infect Dis J,2009,28(10):904-910.
  • 5Canfosa MJ,Perera D et al.Molecular epidemiology of human Enterovirus 71 strains and recent outbreaks in the Asia Pacific Region:Comparative analysis of the VP1 and VP4 genes[J].Emerg Infect Dis,2003,9:461-468.
  • 6Fujimoto TM,Chikahira S et al.Outbreak of central nervous systern disease associated with hand.foot and mouth disease in Japan during the Summer of 2000:detection and molecular epidemiology of enterovirus 71[J].Microbiol Immunol,2002,46:621-627.
  • 7Holger F Rabenau,Matthias Richter et al.Hand,foot and mouth disease:semprevalence of Coxsackie A16 and enterovirus 71 in Germany[J].Med Micro and Immunol,2010,199(1):45-51.
  • 8Mitsuaki Hesoya,Yukihiko Kawasaki et al.Genetic diversity of Coxackie virus A16 associated with hand,foot,and mouth disease epidemics in Japan from 1983 to 2003(J).J Clin Micro,2007,45(1):112-120.
  • 9Munemura TM,Salkusa C et al.Genetic diversity of enterovirus 71 isolated from cases of hand,foot and mouth disease in Yokohama City between 1982 and 2000[J].Arch Virol,2003,148:253-263.

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