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水通道蛋白4抗体的检测方法研究进展 被引量：2

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摘要 视神经脊髓炎（NMO）是一种以视神经和脊髓受累为主要表现的中枢神经系统（CNS）脱髓鞘疾病，多为急性或亚急性起病，可呈单时相病程或复发-缓解的多相病程。以往无特异性检查指标用于诊断该病，主要依据临床表现、MRI和脑脊液检查等确诊。
作者 刘广志 吉良润一
机构地区 北京大学人民医院神经内科 九州大学神经内科
出处 《中华神经科杂志》 CAS CSCD 北大核心 2010年第6期449-450,共2页 Chinese Journal of Neurology
关键词 水通道蛋白4 视神经脊髓炎 检测 抗体 中枢神经系统 脱髓鞘疾病 脑脊液检查 主要表现
分类号 R446.6 [医药卫生—诊断学]
  • 相关文献

参考文献11

  • 1Wingerchuk DM,Hogancamp WF,O' Brian PC,et al.The clinical course of neuromyelitis optica (Devic' s syndrome).Neurology,1999,53:1107-1114.
  • 2Lennon VA,Wingerchuk DM,Kryzer TJ,et al.A serum autoantibody marker of neuromyelitis optica:distinction from multiple sclerosis.Lancet,2004,364:2106-2112.
  • 3Wingerchuk DM,Lennon VA,Pittoek SJ,et at.Revised diagnostic criteria for neuromyelitis optica.Neurology,2006,66:1485-1489.
  • 4Lennon VA,Kryzer TJ,Pittock SJ,et at.IgG marker of opticspinal multiple sclerosis binds to the aquaporin-4 water channel.J Exp Med,2005,202:473-477.
  • 5Rash JE,Davidson KG,Ynsumura T,et al.Freeze-fracture and immunogold analysis of aquaporin-4 (AQP4) square arrays,with models of AQP4 lattice assembly.Neuroscience,2004,129:915-934.
  • 6Furman CS,Gorelick-Feldman DA,Davidson KG,et al.Aquaporin-4 square array assembly:opposing actions of M1 and M23 isoforms.Proc Natl Acad Sci U S A,2003,100:13609-13614.
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  • 9Waters P,Jarius S,Littleton E,et al.Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis.Arch Neurol,2008,65:913-919.
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同被引文献43

  • 1Matsushita T,Matsuoka T,Isobe N,et al.Association of the HLA-DPB1 * 0501 allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders[J].Tissue Antigens,2009,73:171-176.
  • 2Wang H,Dai Y,Qiu W,et al.HLA-DPB1 * 0501 is associated with susceptibility to anti-aquaporin-4 antibodies positive neuromyelitis optica in southern Han Chinese[J].J Neuroimmunol,2011,233:181-184.
  • 3Wang H,Zhong X,Wang K,et al.Interleukin 17 gene polymorphism is associated with anti-aquaporin 4 antibody-positive neuromyelitis optica in the Southern Han Chinese--a case control study[J].J Neurol Sci,2012,314:26-28.
  • 4Kim HJ,Park HY,Kim E,et al.Common CYP7A1 promoter polymorphism associated with risk of neuromyelitis optica[J].Neurobiol Dis,2010,37:349-355.
  • 5Lennon VA,Wingerchuk DM,Kryzer TJ,et al.A serum autoantibody marker of neuromyelitis optica:distinction from multiple sclerosis[J].Lancet,2004,364:2106-2112.
  • 6Lennon VA,Kryzer T J,Pittock S J,et al.lgG marker of opticspinal multiple sclerosis binds to the aquaporin-4 water channel[J].J Exp Med,2005,202:473-477.
  • 7Wingerchuk DM,Lennon VA,Pittock SJ,et al.Revised diagnostic criteria for neuromyelitis optica[J].Neurology,2006,66:1485-1489.
  • 8Wingerchuk DM,Lennon VA,Lucchinetti CF,et al.The spectrum of neuromyelitis optica[J].Lancet Neurol,2007,6:805-815.
  • 9Roemer SF,Parisi JE,Lennon VA,et al.Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis[J].Brain,2007,130:1194-1205.
  • 10Misu T,Fujihara K,Nakamura M,et al.Loss of aquaporin-4 in active perivascular neuromyelitis optica:a case report[J].Tohoku J Exp Med,2006,209:269-275.

引证文献2

二级引证文献4

中华神经科杂志
2010年 第6期

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