甘油长期冷冻保存巩膜及羊膜治疗义眼座暴露

Sclera and amniotic membrane preserved by long-term cryopreservation with glycerol for treating the exposure of hydroxyapatite artificial eye stock

目的:了解甘油长期冷冻保存的巩膜及羊膜在治疗羟基磷灰石义眼座暴露中的效果。方法:羟基磷灰石义眼座植入术后暴露的患者13例13眼,对暴露区清创后以甘油长期冷冻保存的巩膜及羊膜进行修补,术后随访6～12mo,观察巩膜血管化及羊膜上皮化时间。结果:羊膜植片在术后1wk内上皮化13例13眼,巩膜植片在术后10d左右出现血管化,无结膜囊狭窄及义眼座再暴露。结论:甘油长期冷冻保存的巩膜及羊膜用于修补羟基磷灰石义眼座暴露成功率高,修复快,效果较好。

AIM：To evaluate the effect of sclera and amniotic membrane preserved by long-term cryopreservation with glycerol for treating the exposure of hydroxyapatite artificial eye stock. METHODS：Thirteen patients 13 eyes with exposure of hydroxyapatite artificial eye stock were treated by debridement and transplantation with sclera and amniotic membrane preserved by long-term cryopreservation with glycerol. The follow-up was 6 months to 1 year to observe the time of vascularization of sclera and epithelization of amniotic membrane.RESULTS： Thirteen patients 13 eyes were healed well, the time of vasculariztion of sclera was 10 days after operation and the time of epithelization of amniotic membrane was 7 days after operation. No conjunatival sac stenosis or re-exposure of artificial eye stock was observed. CONCLUSION： Sclera and amniotic membrane preserved by long-term cryopreservation with glycerol can be used to patch up the exposure of hydroxyapatite artificial eye stock. It is an effective method with high successful rate.