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胰腺癌肿瘤标志物的研究现状与展望 被引量:5

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摘要 胰腺癌是一种临床发病隐匿、发展迅速、预后极差的恶性肿瘤,因具有较高的侵袭性,且出现临床症状时多数已属晚期,无法手术切除,放化疗效果亦不理想,所以早期诊治是目前提高胰腺癌疗效的关键。肿瘤标志物的研究有助于胰腺癌的早期发现和良恶性病变的鉴别诊断,预测手术或放化疗的治疗效果,判断患者的预后。随着基因组学、蛋白质组学和生物信息学的发展,如何通过血清标本、胰腺组织和胰液找到具有特异性的肿瘤学分子标志物,并评价其在临床应用中的价值,已成为目前研究的主要方向。本文主要介绍近年来胰腺癌肿瘤标志物的研究进展和应用前景。
出处 《中华外科杂志》 CAS CSCD 北大核心 2010年第10期790-793,共4页 Chinese Journal of Surgery
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