摘要
目的:提高Von Hippel-Lindau病的认识及诊治水平。方法:分析1例Von Hippel-Lindau病患者的临床资料、家系调查及基因学研究,并结合文献进行讨论。结果:B超、CT检查发现双肾肿瘤,左侧行保留肾单位手术,右侧行肾癌根治性切除术,术后病理均提示透明细胞癌。随访20月,患者因全身衰竭死亡。结论:影像学检查、家系调查及基因检测可诊断此病,高危家族的基因检测筛选及早期手术是治愈本病的关键。
Objective : To explore the methods of diagnosis and treatment for Von Hippel - Lindau disease. Methods: A patient with Von Hippel - Lindau disease was reported. Familial and genetic researches was presented and discussed with reviewing the literature. Results: The diagnosis of tumor of kidney was established by B - ultrasonoggra- phy, CT. Patient was treated by surgery. The pathologic test showed renal cell carcinoma. After twenty months follow up, patient died. Conclusion:The diagnosis depends on imaging studies, familial and genetic researches. Screening in families with genetic tests and earlier surgical therapy are very important for the treatment.
出处
《现代肿瘤医学》
CAS
2010年第6期1171-1172,共2页
Journal of Modern Oncology