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褪黑素对链脲佐菌素所致大鼠胰岛β细胞结构及功能损伤的保护作用 被引量:1

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摘要 链脲佐菌素(STZ)对胰岛β细胞的毒性作用与氧化应激有关。褪黑素(melatonin,MLT)是一种有效抗氧化剂。研究表明,褪黑素可明显降低STZ大鼠胰腺内应激氧化水平,降低STZ所致的大鼠高血糖水平。本研究侧重观察MLT对STZ大鼠胰岛β细胞结构及功能的保护作用。
出处 《中华内科杂志》 CAS CSCD 北大核心 2010年第6期514-515,共2页 Chinese Journal of Internal Medicine
基金 基金项目:国家重点基础研究发展计划(2005CB523304)
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