支架成形术治疗椎动脉颅内段和基底动脉狭窄17例临床观察

Stenting for intracranial vertebral artery and basilar artery stenosis

目的评估症状性椎动脉颅内段、基底动脉狭窄患者经皮血管内支架成形术(PTAS)治疗的安全性和有效性。方法17例症状性椎动脉颅内段及基底动脉狭窄患者,狭窄程度在50%以上且规范的内科药物治疗无效,给予PTAS治疗,术后常规给予抗凝、抗血小板聚集、降脂药物。结果17例患者20处狭窄行PTAS,所有的病例手术均取得成功,没有严重并发症,术后即刻造影残存狭窄平均在10%以下,病人平均随访6.8个月(3～10个月),有1例患者出现再狭窄(狭窄程度>50%),所有患者均无缺血症状发作。结论PTAS治疗椎动脉颅内段及基底动脉狭窄是安全和有效的。

Objective To evaluate the safety and efficacy in the treatment of symptomatic intracranial vertebral artery and basilar artery stenosis. Methods Seventeen patients core suffered with symptomatic intracranial vertebral and basilar artery stenosis, the stenosis was more than 50% and had failed in regalar medical therapy. All of the lesion were treated with PTAS, we regalarly gave continual anticoagulation and anti-platelet after PTAS. Results Seventeen patients with twenty lesions were treated with stent-assisted angioplasty successfully. Without severe complications, the mean stenosis rate of postoperation was less than 10%. During the follow-up for 6.8months（3-10months）,only one case suffered restenosis but no symptom of ischemia recurred. Conclusion PTAS is safe and effective in the treatment of symptomatic intracranial vertebral artery and basilar artery stenosis.