新疆和田地区维吾尔族人群血脂水平与踝臂指数、肱-踝脉搏波速度关系

Relationship of blood lipid with ankle-brachial index and brachial-ankle pulse wave velocity in Uygur nationality in Hetian of Xinjiang

目的:探讨新疆和田地区维吾尔族自然人群血脂水平与肱-踝脉搏波速度、踝臂指数的关系。方法:采用整群抽样方法进行调查,有效样本量2366例。记录一般情况,测定相关生化指标及踝臂指数、肱-踝脉搏波速度,分析不同年龄不同性别人群血脂异常情况与踝臂指数、肱-踝脉搏波速度的关系。结果:踝臂指数、肱-踝脉搏波速度、三酰甘油、低密度脂蛋白胆固醇在不同年龄组差异均有统计学意义(P<0.05),在性别上差异无统计学意义(P>0.05)。肱-踝脉搏波速度与总胆固醇、低密度脂蛋白胆固醇呈正相关,踝臂指数与血脂代谢异常无相关性。结论:年龄为踝臂指数、肱-踝脉搏波速度主要危险因素,血脂紊乱影响动脉顺应性降低,使肱-踝脉搏波速度值增高。

Objective To observe the relationship of blood lipid with ankle-brachial index and brachial-ankle pulse wave velocity in Uygur nationality in Hetian,Xinjiang.Methods A total of 2 366 volunteers were enrolled in the study.All the patients were measured the related indexes,ankle-brachial index and brachial-ankle pulse wave velocity to analyze the relationship of abnormal lipid with ankle-brachial index and brachial-ankle pulse wave velocity among different ages and between genders.Results There were significant differences in ankle-brachial index,brachial-ankle pulse wave velocity,total cholesterol and low density lipoprotein cholesterol among the different ages（P〈0.05）.But no differences were found between genders（P〉0.05）.Brachial-ankle pulse wave velocity was positively correlated to total cholesterol and low density lipoprotein cholesterol.Ankle-brachial index was not correlated to the lipid metabolism disorder.Conclusion The old age is the most important risk factor for ankle-brachial index and brachial-ankle pulse wave velocity.The blood lipid metabolism disorder decreases arterial compliance and increases brachial-ankle pulse wave velocity.