三维稳态破坏性梯度回返采集在颅脑疾病诊断中的应用(兼与二维自旋回波T_1WI对比研究)

Application of 3D SPGR in cerebral diseases: comparative study of 3D SPGR and 2D SE T 1WI after enhancement

目的前瞻性探讨三维稳态破坏性梯度回返采集（ｔｈｒｅｅｄｉｍｅｎｓｉｏｎａｌｓｐｏｉｌｅｄｇｒａｄｉｅｎｔｒｅｃａｌｅｄａｃｑｕｉｓｉｔｉｏｎｉｎｓｔｅａｄｙｓｔａｔｅ，３ＤＳＰＧＲ）在颅脑疾病中的应用价值，并且增强后与二维自旋回波（２ＤＳＥ）Ｔ１ＷＩ作对比分析。方法１７例病变，采用ＧＥ１．５Ｔ扫描机，增强后行２ＤＳＥＴ１ＷＩ及３ＤＳＰＧＲ轴面扫描，并进行对比研究。结果⑴除动脉瘤外，２ＤＳＥＴ１ＷＩ较３ＤＳＰＧＲ多发现１３个病变，且两者描述主体病变强化程度相当；⑵２ＤＳＥＴ１ＷＩ的信噪比、对比度及对比噪声比分别是３ＤＳＰＧＲ的１．５７、１．２及１．９７倍；⑶３ＤＳＰＧＲ图像后处理技术能显示２０例病变累及血管的各种表现；⑷３ＤＳＰＧＲ显示大动脉瘤较ＭＲ血管造影更完美。结论在颅脑疾病增强检查中，３ＤＳＰＧＲ具有许多２ＤＳＥＴ１ＷＩ无法比拟的优越性，有取代２ＤＳＥＴ１ＷＩ的可能。

Objective To evaluate the utility of three dimensional spoiled gradient recalled acquisition in steady state(3D SPGR) imaging in the cerebral diseases, and compare 2D SE T 1WI with 3D SPGR after enhancement. Methods 117 patients were studied with a 1.5T MRI scanner. After enhancement,2D SE T 1WI and 3D SPGR were performed and compared. Results (1)2D SE T 1WI detected 13 more lesions than 3D SPGR, and the degree of main lesion enhancement was equal on the two series. (2)SNR、C and CNR on 2D SE T 1WI were much greater than those of 3D SPGR, increasing by an average of 57%,20% and 97% respectively.(3)3D SPGR imaging with MPR and MIP depicted vascularity related to lesions in 20 cases.(4)6 cases of large aneurysms (8 lesions) were visualized much more clearly on 3D SPGR technique than on MRA. Conclusions Enhanced 3D SPGR plays an important role in the cerebral diseases, it is superior to 2D SE T 1WI in many aspects. It may replace 2D SE T 1WI in the future.