泮托拉唑联合醋氨己酸锌治疗消化性溃疡的疗效观察

Divides the request to pull zuo the union vinegar ammonia caproic acid zinc treatment digestive ulcer＇s curative effect observation

目的：评价泮托拉唑联合醋氨己酸锌治疗消化性溃疡，对溃疡愈合质量的影响。方法：将120例消化性溃疡伴有幽门螺杆菌（Hp）感染活动性溃疡患者随机分为试验组和对照组，两组均先给予标准三联疗法根除Hp。1周后试验组给予泮托拉唑40mg、1次／d，醋氨己酸锌300mg、3；k／d；对照组给予泮托拉唑40mg、1；k／d继续治疗，十二指肠溃疡疗程4周，胃溃疡疗程6周后观察内镜下溃疡愈合率、Hp转阴率、愈合S2期的获得率。结果：疗程结束后，两组病例溃疡愈合率和Hp根除率比较差异无显著性（P〉O．05）。试验组溃疡愈合S2期获得率显著高于对照组（P〈0．05）。结论：泮托拉唑联用醋氨己酸锌治疗消化性溃疡是一种安全有效实用的方案，醋氨己酸锌在提高溃疡愈合质量上有重要的作用。

Objective： Appraises divides the request to pull zuo the union vinegar ammonia caproic acid zinc treatment digestive ulcer, to ulcer cicatrization quality influence. Methods： Is accompanied by 120 example digestive ulcer the pylorus spiral bacillus （Hp） infection activity ulcer patient to divide into stochastically the experimental group and the control group, two groups first give the standard trigeminy therapy to eradicate Hp. 1 week later experiments the group to give divides the request to pull zuo 40mg, 1/d, vinegar ammonia caproic acid zinc 300rag, 3 /d; The control group gives divides the request to pull zuo 40mg, 1 /d to continue to treat, duodenal ulcer treatment course 4 weeks, gastric ulcer treatment course 6 weeks later in observes under the mirror ulcer recovery rate, Hp to transfer cloudy rate, heals the S2 time to obtain rate. Result： After the treatment course had ended, two group of case ulcer recovery rate and the Hp eradication rate comparison difference does not have the significance （P〉0.05）. Experimental group ulcer heals S2 time acquisition rate obviously to be higher than the control group （P（P〈0.05）. Conclusion=Divides the request to pull zuo unites with the vinegar ammonia caproic acid zinc treatment digestive ulcer is one kind of security effective practical plan, the vinegar ammonia caproic acid zinc in improves in ulcer cicatrization quality to have the vital role.