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Cystatin C、Hcy和高敏C反应蛋白对不稳定斑块的预测意义 被引量:8

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摘要 目的探讨ACS患者血清Cystatin C、Hcy和Hs-CRP的浓度变化与斑块稳定性的关系。方法分为不稳定性心绞痛(UAP)组、发病48h内的急性心肌梗死(AMI)组和对照组。同步测定血清Cystatin C、HsCRP和Hcy。结果 Hs-CRP和Hcy在UAP组和AMI组均比对照组升高(P<0.05),而且AMI组与UAP组比较也存在显著差异(P<0.05)。UAP组Cys-tatin C较对照组升高(P<0.05),AMI组比对照组降低(P<0.05)。直线相关分析显示Hcy和InHs-CRP呈正相关(P<0.01)。UAP组中血清Cystatin C浓度与Hcy、Hs-CRP呈正相关性(P<0.05),而在AMI组则没有相关性。结论血清Hcy和Hs-CRP水平具有良好的相关性,均随动脉粥样斑块不稳定程度的加重而升高。联合检测2者可协助了解病情,并为指导治疗及判断预后提供依据。血清Cystatin C浓度变化在一定程度上也可以反映动脉粥样斑块的稳定性。
出处 《实用临床医药杂志》 CAS 2010年第5期88-91,共4页 Journal of Clinical Medicine in Practice
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