咳嗽变异型哮喘60例诊治分析

Diagnosis and Treatment Analysis of 60 Cases with Cough Variant Asthma

目的分析咳嗽变异型哮喘(CVA)的临床特点、诊治状况,总结治疗体会,旨在提高诊治水平,降低误诊率。方法总结支气管舒张试验阳性的CVA患者60例的临床特点,随机分为两组,对照组和观察组。对照组:采用常规治疗,如吸入糖皮质激素、口服支气管解痉剂等;观察组:在常规治疗的基础上,雾化吸入低分子肝素钙。比较用药后咳嗽、肺功能的变化。结果观察组的临床总有疗率明显高于对照组(P<0.01);肺功能较对照组有所显著改善(P<0.05)。结论在常规治疗基础上雾化吸入低分子肝素钙对CVA疗效显著,具有临床应用价值。

Objective To analyze the clinical characteristics and diagnosis and treatment situation of cough variant asthma. We summarize the treatment experiencing to shoot for a higher diagnosis and treatment level and a lower misdiagnosis rate. Methods To summarize the clinical feature of 60 cases with positive bronchial dilation test of cough variant asthma. The 60 cases were divided into two groups randomly： the control group and observe group. The control group： conventional therapy, for example, inhaled corticosteroids and antispasmodic. The observe group： bases on the conventional therapy, neb nebulised medication low molecular weight heparin calcium. To compare the change of cough and pulmonary function. Results The clinical total effective rate of the observe group was much higher than that of control group（P〈 0.01）. The pulmonary function of observe group had noticeable improvements compared with control group （P〈0.05）.Conclusion Based on conventional therapy, neb nebulised medication low molecular weight heparin calcium has obvious effect to cough variant asthma. It has clinical application value.