大小剂量缩宫素用于晚期妊娠引产的效果观察

Observation on effect of labor induced with high and lowl dose of oxytocin in late gestation

[目的]比较大小剂量缩宫素静脉输注对晚期妊娠引产的效果。[方法]将151例孕妇按住院时间分成实验组和对照组,两组病人用不同的剂量用于晚期妊娠引产,即实验组孕妇(76例)使用4%的缩宫素脉冲式给药,对照组孕妇(75例)使用0.5%缩宫素引产。[结果]实验组缩宫素输入总量、达到有效宫缩时间与对照组比较差异有统计学意义(P<0.05);实验组24 h阴道分娩率、引产成功率高于对照组(P<0.05);[结论]大剂量缩宫素脉冲式给药能有效提高缩宫素引产的成功率,用药安全,不增加胎儿宫内窘迫率。

Objective： To compare the effect of labor induced with intravenous infusion of high and low dose of oxytocin in late gestation. Methods：A total of 151 pregnant women were divided into test and control group based on the length of stay. Test group of 76 pregnant women were given 4% oxytocin in pulsed- wave mode. Another 75 pregnant women in control group with were given 0.5 % oxytocin. Results：There were statistical significant differences between in terms of the total amount of infused oxytocin and the time to achieve effective uterine contraction between test and control group pregnant （P〈0. 05）. The rate of vaginal delivery within 24 hours and the success rate of labor induetion of test group cases were higher that of control group cases （P〈0.05）. Conclusion： High dose of oxytocin given in pulsed -wave mode for induced labor of pregnant women in late gestation can raise the success rate of labor induction. It is safe. And it can not increase the rate of fetal distress.