超声微泡造影剂的安全性及黑框警告风波

Safety and Black Box Warning for Microbubble Ultrasound Contrast Agent

超声造影剂能明显改善超声心动图的图像质量,有重要的临床实用价值。最新研究显示,其严重不良事件发生率很低,临床获益远超过其风险。但是,有关超声造影剂生物学效应的研究仍在进行中,超声造影在抗栓及载药治疗等新领域的应用前景和安全性也需要评价。

Contrast-enhanced ultrasound can significantly improve the image quality of echocardiography,there are important clinical practical value.The latest studies show the low rate of serious adverse events,and clinical benef it far more than its risks.However,the biological effects of ultrasound contrast agent study is still underway,the prospects and safety of ultrasound and angiography in the antithrombotic treatment and drug delivery application needs assessment.